Risk factors and consequences of stroke
Principal investigator; Lindgren, Arne, Professor, MD/PhD
Clinical speciality: Neurology
Phone: ++4646171424
Co-workers: B Norrving, G Andsberg, AC Jönsson Neurology; H Luthman, Mol Genetics; U Kristoffersson, Clin Genetics; P Höglund, RSKC; C Nerbrand, Community Med. PhD students: H Lövkvist, H Mazlumolhosseini. Physiotherapist I Lindgren
International networks: Massachusetts General Hospital Boston
Johns Hopskins Baltimore
St George's Hospital London
This stroke research program includes translational research on molecular genetic level, stroke risk factors, acute treatment and acute diagnostic evaluation of stroke, epidemiology of stroke, nursing and life after stroke.
Our multidisciplinary team work with neurologist, nurse specialist, physiotherapist, biostatistician, GP, clinical geneticist, molecular geneticist and methodological expertise is based on the first-ever stroke patients included in the Lund Stroke Register. More than 3200 stroke patients have been included. The type of stroke is characterised and risk factors including genetic causes are examined. We also assess from an epidemiological point of view if stroke incidence and characteristics (including survival) are changing over time. Follow-up of the patients regarding pain (including shoulder pain), nutritional status, quality of life and secondary stroke prevention is performed. Possibilities to treat stroke patients in primary care units are studied. Causes of intracerebral haemorrhage are examined as well as survival after intracerebral haemorrhage. Recovery after stroke is also studied. We are co-operating internationally in the International Stroke Genetics Consortium.
5 recent original publications
Lindgren A, Lövkvist H, Hallström B, Höglund P, Jönsson A-C, Kristoffersson U, Luthman H, Petersen B, Norrving B
Prevalence of stroke and vascular risk factors among first-degree relatives of stroke patients and control subjects. A prospective consecutive study
Cerebrovasc Dis. 2005; 20: 381-7
Jonsson AC, Lindgren I, Hallstrom B, Norrving B, Lindgren A
Common genetic variants on chromosorne 9p21 confers risk of ischemic stroke: a large-scale genetic association study.
Circulation: Cardiovascular Genetics. 2009; 2: 159-164
Jönsson AC, Lindgren I, Hallström B, Norrving B, Lindgren A
Determinants of quality of life in stroke survivors and their informal caregivers
Stroke. 2005; 36: 803-8
Hallstrom B, Jonsson AC, Nerbrand C, Norrving B, Lindgren A
Stroke incidence and survival in the beginning of the 21st century in southern sweden. Comparisons with the late 20th century and projections into the future
Stroke. 2008; 39: 10-15
Hallstrom B, Jonsson AC, Nerbrand C, Petersen B, Norrving B, Lindgren A
Lund stroke register: Hospitalization pattern and yield of different screening methods for first-ever stroke
Acta Neurol Scand. 2007; 115: 49-54
Further publications here (new window)
Financing/year
| Total financing: | MSEK | Gov grant for clinical research ("ALF"): | MSEK | |
| Total external financing: | MSEK | Natl and intl prioritized grants: | MSEK |